Ascending thoracic aorta aneurysms (aTAA) represent a severe threatening condition in the modern clinical landscape. The risk of aTAA rupture is usually higher in patients with bicuspid aortic valve (BAV) with respect to tricuspid valve (TAV). It is known that aneurysm formation is associated with changes in the content and architecture of elastin and collagen fibers within the aortic tissue. Moreover the effect of morphological parameters has been investigated and
correlated with maximum wall stress on thoracic aneurysms. The aim of this study is to investigate the histomechanical and morphological characteristics of aTAA to better understand the relationship between all the calculated parameters.